解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::The biological control of schistosomiasis has already proven its efficiency in several habitats in the Caribbean area. Two main types of biological control agents, either trematode parasites or competitor snails have been studied and tested against the snail hosts of schistosomiasis in this region. The first one, Ribe...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/s0001-706x(00)00123-6
更新日期:2000-10-23 00:00:00
abstract::The several steps in the pathway for the biosynthesis of fibrillar collagen are reviewed to illustrate potential sites for the chemotherapeutic control of fibrosis. Particular emphasis is placed upon the properties and inhibition of lysyl oxidase, the enzyme which initiates the covalent crosslinking of extracellular c...
journal_title:Acta tropica
pub_type: 杂志文章,评审
doi:10.1016/s0001-706x(00)00128-5
更新日期:2000-10-23 00:00:00
abstract::Gut lectins of the insect vectors play important roles in the transmission of pathogens. Galactosamine, a sandfly midgut lectin inhibitor, was previously demonstrated to increase the intensity of Leishmania infection in sandflies; it was suggested that this was due to the inhibition of sandfly midgut lectin. However, ...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/s0001-706x(00)00105-4
更新日期:2000-10-02 00:00:00
abstract::We have retrospectively studied the seroprevalence of the human immunodeficiency virus (HIV) in Guinea-Bissau in a sample of sera collected from the whole country in 1980. We tested a total of 1248 individuals and found 11 individuals who were seropositive for HIV-2 but there were no HIV-1 seropositive samples. The me...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/s0001-706x(00)00096-6
更新日期:2000-09-18 00:00:00
abstract::Slaughterhouse surveys are important in the detection and management of zoonotic diseases. Routine reports from the Kumasi slaughterhouse, in the Ashanti region of Ghana, include cases of zoonotic diseases. Due to its location and size, Kumasi is the major cattle market and an important transit point for cattle trade ...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/s0001-706x(00)00083-8
更新日期:2000-07-21 00:00:00
abstract::The aetiology of zoonotic infections embraces organisms from every branch of the microbial world. In addition, zoonoses must be considered as a truly global problem, both in terms of their distribution and the measures required for their control. Within the UK, zoonotic disease is considered to be less frequent than i...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/s0001-706x(00)00093-0
更新日期:2000-07-21 00:00:00
abstract::In sub-Saharan Africa, tick infestation and tick-borne infections together with tsetse-transmitted trypanosomosis arguably constitute the main parasitological disease complex constraining livestock production. Resistance to tick attack and tick-borne micro-organisms (TBMs) varies among different breeds of cattle. The ...
journal_title:Acta tropica
pub_type: 杂志文章,评审
doi:10.1016/s0001-706x(00)00063-2
更新日期:2000-05-31 00:00:00
abstract::The analysis of three recombinant clones containing the histone H2A locus isolated from a genomic library of Trypanosoma cruzi DNA shows that the H2A gene loci are formed by 1.2 and 0.76 kb long intercalated units organized in a head-to-tail tandem array. The difference in length between the two gene units is due to t...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/s0001-706x(00)00061-9
更新日期:2000-03-25 00:00:00
abstract::The morphological and anatomical characters applied to determine species identity in the Bulinus africanus group species are insufficient to unambiguously discriminate between arbitrary species of given populations. In order to solve this problem, four snail populations from Kenya have been investigated morphologicall...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/s0001-706x(99)00086-8
更新日期:2000-02-25 00:00:00
abstract::While Burkholderia pseudomallei, the causative agent of melioidosis, is becoming increasingly recognized as a significant cause of morbidity and mortality in regions to which it is endemic, no licensed vaccine preparation currently exists for immunization against the disease. Therefore, one of the primary goals of our...
journal_title:Acta tropica
pub_type: 杂志文章,评审
doi:10.1016/s0001-706x(99)00071-6
更新日期:2000-02-05 00:00:00
abstract::The gastrointestinal manifestations of acute symptomatic uncomplicated falciparum malaria were studied in 184 consecutive children aged from 6 months to 15 years. Vomiting was the most common and epigastralgia the least common presenting symptom. Peripheral parasite density was higher in children who were vomiting tha...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/s0001-706x(99)00043-1
更新日期:2000-01-05 00:00:00
abstract::The efficacy of a 5-day treatment with intramuscular artemether (3.2-mg/kg loading dose followed by 1.6 mg/kg daily) was compared to that of the standard 7-day treatment with quinine (20-mg/kg loading dose followed by 10 mg/kg every 8 h) in a randomised clinical trial including 103 children aged 12-60 months with cere...
journal_title:Acta tropica
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0001-706x(99)00031-5
更新日期:1999-10-15 00:00:00
abstract::A total of 22,982 sandflies representing six species were collected using sticky (oiled) paper traps in Badrood rural district, Natanz county from May 1995 to May 1996. Phlebotomus papatasi was the predominant species. The average indoor resting density of P. papatasi ranged from 11.8 (May 1995) to 135.8 per 10 traps ...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/s0001-706x(99)00038-8
更新日期:1999-10-15 00:00:00
abstract::The role of phospholipids (PLs) in the signal transduction pathways that are activated by a mitogenic stimulus (foetal calf serum) in Trypanosoma cruzi epimastigotes (EPI) was investigated. Only phosphatidylinositol-bis-phosphate was significantly altered in this process. Other phosphoinositides, including major PLs s...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/s0001-706x(99)00016-9
更新日期:1999-07-30 00:00:00
abstract::The preference of Triatoma infestans for shelters at different temperatures or relative humidities (RH) was tested in laboratory assays. The insects preferred refuges at a temperature of 34 degrees C rather than 26 degrees C, and chose to stay in refuges with an RH of 20% rather than 80%. Temperature and RH records ma...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/s0001-706x(98)00094-1
更新日期:1999-04-30 00:00:00
abstract::Domestic reinfestations by triatomine bugs were monitored after application of deltamethrin and apparent elimination of Triatoma infestans in Amama and other nearby rural villages, north-west Argentina, from 1992 to 1996. The five methods used were sensor boxes, sheets of pink typing-paper, timed manual catches by a s...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/s0001-706x(98)00096-5
更新日期:1999-03-15 00:00:00
abstract::By standardized interviews of people in 23 rural villages, in the Oio region of Guinea Bissau, we collected data on which plant species and plant derived products or methods people use to reduce mosquito biting activity. The following plants were used to reduce numbers of mosquitoes indoors at night: fresh or smoulder...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/s0001-706x(98)00083-7
更新日期:1999-01-15 00:00:00
abstract::Echinococcosis, a disease caused by infection with the larval stage of a tapeworm parasite of the genus Echinococcus, is of major socio-economic importance, and studying genetic variability within and between Echinococcus populations has important implications for disease control and epidemiology. Various DNA approach...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/s0001-706x(98)00052-7
更新日期:1998-09-15 00:00:00
abstract::Using degenerate oligonucleotide primers based on conserved active site residues, we have isolated a cDNA encoding an aspartic protease from the nematode parasite Strongyloides stercoralis, an important, enteric pathogen of humans. cDNAs encoding the aspartic protease were isolated from the infective, third stage larv...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/s0001-706x(98)00050-3
更新日期:1998-08-15 00:00:00
abstract::The in vitro metacyclogenesis of a visceral (VL) and cutaneous (CL) human strain of Leishmania infantum was monitored in order to find out the kinetics of this process and the in vitro infective capacity for macrophages of the metacyclic promastigotes developed. To identify, enumerate, and separate the metacyclic popu...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/s0001-706x(98)00041-2
更新日期:1998-07-30 00:00:00
abstract::We report the pattern of infection of Glossina pallidipes with Trypanosoma vivax and T. congolense at a site in the Coast region of eastern Tanzania, studied between November 1993 and December 1994. Of the 2315 flies dissected 114 (4.9%) were T. congolense positive, 77 (3.3%) were T. vivax positive and 2 (0.1%) were T...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/s0001-706x(98)00013-8
更新日期:1998-06-30 00:00:00
abstract::The drawback of existing techniques for obtaining intact granulomas and granuloma cells have been, (1) lack of clean intact granulomas without adhering liver tissues, (2) isolating inadequate numbers of clean intact granulomas, and (3) obtaining low numbers of viable granuloma cells from the granulomas. This work aims...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/s0001-706x(98)00034-5
更新日期:1998-06-30 00:00:00
abstract::Benflumetol, a novel antimalarial compound belonging to the fluorenes (2,3-benzindenes), has high blood schizontocidal activity, in vitro and in vivo, against mammalian plasmodia, including chloroquine-resistant Plasmodium falciparum. Due to its molecular structure benflumetol occurs in the dextrorotatory and the laev...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/s0001-706x(97)00141-1
更新日期:1998-06-15 00:00:00
abstract::30 Trypanosoma cruzi strains isolated from chronic chagasic patients were studied at the genotype level by RAPD with arbitrary primers and SSR-PCR analysis. The genetic distance of strains was measured by the percentage of unshared bands. The results showed that the strains isolated from chronic patients from differen...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/s0001-706x(97)00122-8
更新日期:1998-05-01 00:00:00
abstract::The small mammal fauna of coffee plantations in SW Colombia was surveyed to determine which of the species present were infected with parasites of the Leishmania (Viannia) braziliensis complex and might therefore act as reservoirs of human cutaneous leishmaniasis. Fifty animals of seven different species were captured...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/s0001-706x(97)00114-9
更新日期:1998-03-01 00:00:00
abstract::Improving immunization coverage is vital to promoting child health and reducing childhood diseases and deaths. In spite of being actively promoted as a major public health intervention for national development since the late 1970s, immunization coverage in Ghana remains low. We investigated factors that influence atte...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/s0001-706x(97)00094-6
更新日期:1997-12-01 00:00:00
abstract::Peripheral blood smears of 20 patients with Indian Kala-azar (KA) were collected throughout the day and night and examined for presence of Leishmania amastigotes. Amastigotes were detected in 46% of peripheral blood samples taken during the day (08:00-17:00 h) and 66% and during the night (18:00-07:00 h). This differe...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/s0001-706x(97)00104-6
更新日期:1997-12-01 00:00:00
abstract::As strictly haematophagous insects, tsetse flies feed on a wide variety of wild and domestic animals. Although these are mainly mammals, some tsetse species also feed on reptiles. The present study investigated whether the odours of several potential natural tsetse hosts may be used as novel attractants to improve the...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/s0001-706x(97)00083-1
更新日期:1997-11-01 00:00:00
abstract::Cell lysates from 16 strains of eight Leishmania species were used to test haemagglutination activity (HA) against a variety of RBC. HA was detected using native or neuraminidase-treated rabbit RBC; it was found in promastigotes of all the Leishmania strains tested and in axenic amastigotes of L. mexicana. The HA was ...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/s0001-706x(97)00069-7
更新日期:1997-10-14 00:00:00
abstract::This paper reviews various imaging techniques in different organs. Ultrasound is the most popular and readily available technique. Special emphasis is given to computerized tomography (CT) and magnetic resonance imaging (MRI) findings and their advantages for a confident diagnosis and treatment. ...
journal_title:Acta tropica
pub_type: 杂志文章,评审
doi:10.1016/s0001-706x(97)00052-1
更新日期:1997-09-15 00:00:00
abstract::Extracts prepared from 15 rare Tanzanian medicinal plants were tested for their in vitro antitrypanosomal activity against human pathogenic trypanosomes (Trypanosoma brucei rhodesiense). Of 37 extracts investigated, two were found to have strong activity with IC50 values below 1 microgram/ml and ten extracts revealed ...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/s0001-706x(97)00034-x
更新日期:1997-08-01 00:00:00
abstract::The study aimed to establish if there was any relationship between the blood group of the human host and schistosomiasis prevalence, intensity, incidence and related organ pathology. Urine and stool specimens were collected from the 735 school children attending a rural school in Zimbabwe to determine the Schistosoma ...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/s0001-706x(97)00671-2
更新日期:1997-05-30 00:00:00
abstract::Plasmodium falciparum (F32) parasites were exposed to artemisinin and quinine for 3 and 4 h, respectively, once or twice daily and for 3, 5 or 7 days. Between the peaks the parasites were exposed to trough concentrations. Continuous drug exposure was also assessed for comparison. After drug exposure, the cultures were...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/s0001-706x(96)00565-7
更新日期:1997-04-30 00:00:00
abstract::A survey was undertaken between November 1994 and January 1995 to assess the knowledge and practice with respect to malaria of 1946 randomly selected households in endemic urban and rural areas of Hormozgan, Kerman and Sistan and Baluchistan Provinces, southeast Iran. Knowledge of inhabitants was relatively poor in th...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/s0001-706x(96)00609-2
更新日期:1997-04-15 00:00:00
abstract::This review paper examines the evidence from published and previously unpublished sources for the efficacy and safety of albendazole (ABZ) obtained in the last 12 years. Benzimidazole treatment alone is not ideal, requiring prolonged administration over many weeks, with an unpredictable outcome in terms of response ra...
journal_title:Acta tropica
pub_type: 杂志文章,评审
doi:10.1016/s0001-706x(96)00640-7
更新日期:1997-04-01 00:00:00
abstract::Antibodies to the Pfs2400 gametocyte antigen have been shown to inhibit the development of Plasmodium falciparum in anophelines and therefore this antigen is a candidate for a transmission-blocking vaccine. To test seasonal variation of these antibodies under field conditions, sera from 72 individuals were collected t...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/s0001-706x(96)00620-1
更新日期:1997-02-01 00:00:00
abstract::Schistosomiasis of the lower female reproductive tract manifests itself in a broad spectrum of clinical features. However, clinical and histopathological findings have never been studied in a synoptic manner. Based on the assumption that any type of pathology present in the female reproductive tract is the expression ...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/s0001-706x(96)00027-7
更新日期:1996-12-30 00:00:00
abstract::The Marrara syndrome, like Halazoun in Lebanon, is a hypersensitivity reaction of the upper respiratory tract and buccopharyngeal mucosa to nymphs of Linguatula serrata. The condition follows the consumption of Marrara which consists of raw liver, lungs, trachea and rumen of goats and sheep infected with larvae of L. ...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/s0001-706x(96)00017-4
更新日期:1996-12-16 00:00:00
abstract::Proteins in Schistosoma haematobium infected human urine were concentrated by precipitation with saturated ammonium sulphate 50% (v/v) and various fractions obtained at different stages of precipitation tested for presence of schistosome antigens (ShAgs) by dot-ELISA. The protein fraction (UP2S) obtained following two...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/s0001-706x(96)00040-x
更新日期:1996-10-01 00:00:00
abstract::The food selection behaviour of two fish species indigenous to Zimbabwe (Tilapia rendalli and Sargochromis codringtoni) was studied under laboratory conditions with a view to considering them as biological agents for snail control. Six glass aquaria were set up and divided into two sets each with two aquaria. One S. c...
journal_title:Acta tropica
pub_type: 杂志文章
doi:10.1016/0001-706x(95)00144-4
更新日期:1996-05-01 00:00:00